Abstract Background Metastases are the major cause of cancer-related morbidity and mortality.By the time cancer cells detach from their primary site to eventually spread to distant sites, they need to acquire the ability to survive in non-adherent conditions and to proliferate within a new microenvironment in spite of stressing conditions that may
PurposeTo assess the non-inferiority of pegfilgrastim versus filgrastim in speeding the recovery of polymorphonuclear cells (PMN) in pediatric patients who underwent autologous peripheral blood stem cell transplant (PBSCT).MethodsThe sample size of this randomized, multicenter, phase III study, was calculated assuming that a single dose of pegfilgr
Abstract Background The incidence of pain disorders in women is higher than in men, making gender differences in pain a research focus.The human insular cortex is an important brain hub structure for pain processing and is divided into several subdivisions, serving different functions in pain perception.Here we aimed to examine the gender differenc
The mining of oil sands in Alberta, Canada is a large-scale disturbance that requires land reclamation to equivalent land capability.Cover soils used for upland forest reclamation are forest floor mineral-mix (FFM) sourced from upland forest ecosystems and peat mineral-mix (PM) sourced from lowland ecosystems.Spatial heterogeneity and quantity of s
This article explores the significance of managerialism as a concept for thinking about projects of state reform across the last forty years.Making particular reference to the United Kingdom and its role in the proliferation of the New Public Management, the article suggests that managerialism (as an ideology) and managerialisation (as a process of